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Nanoscale Characterization of Iron and Calcium in the Alzheimer’s Brain

The amyloid plaques that accumulate in Alzheimer’s disease contain stores of iron. Using scanning transmission x-ray microscopy, researchers have characterized the iron’s chemical states in unprecedented detail. Their nanoscale analysis revealed excessive chemical reduction of the iron, which can release damaging free radicals. Read more »

New Manganese Materials Bolster Cathode Capacity

The most expensive component of a battery, the cathode, requires rare transition metals like cobalt. Previous attempts to replace cobalt with inexpensive and non-toxic manganese delivered insufficient performance. Now, researchers have optimized the composition of high-energy-density, high-capacity manganese-based cathodes. Read more »

2018 Shutdown Recap

Users have returned to the ALS after a six-week summer shutdown. Among the many small and large changes, we performed a major upgrade of the HVAC system that will stabilize the temperature throughout the experimental hall. None of the changes will affect the delivery of light. Read more »

Jeff Neaton, Energy Sciences Associate Laboratory Director

Jeff Neaton is the Energy Sciences Associate Laboratory Director. He joined Berkeley Lab as a postdoc at the Molecular Foundry in 2003 before becoming a staff scientist. While maintaining his research program, he has also taken on many leadership responsibilities at the Lab. Read more »

Open and Shut: Pain Signals in Nerve Cells

Researchers used x-ray data to define the structure of a closed protein gate important for neuronal signaling. Comparing the closed gate with previously known structures of the same gate when open, researchers now have a comprehensive picture of proton-dependent channels in neurons. Read more »

Bjoern Enders, Physics Postdoctoral Fellow

Bjoern Enders joined the ALS as a postdoc in July 2016. He first worked on Beamline 5.3.2.1 before moving to Beamline 7.0.1 (COSMIC) when 5.3.2.1 was disassembled and the ptychography program was moved in the summer of 2017. His research is part of the NSF Science and Technology Center STROBE. Read more »