Molecular-beam experiments with isomer-selective photoionization via a targeted, vinylacetylene-mediated gas-phase reaction of aromatic helicenyl radicals coupled with electronic structure calculations and astrochemical modeling reveal an elegant synthetic route to racemic helicenes – ortho-fused polycyclic aromatic hydrocarbons (PAHs), in which benzene building blocks form helically-shaped molecules. Read more »
All News & Updates
Surface Charge and Nanoparticle Chromophore Coupling to Achieve Fast Exciton Quenching and Efficient Charge Separation in Photoacoustic Imaging (PAI) and Photothermal therapy (PTT)
Organic semiconductor nanoparticles (OSNs) convert absorbed light into heat, and are commonly used in photothermal therapy and photoacoustic imaging. Here, the OAN, Y6, is shown to form strong intermolecular packing, manipulated by surface charge under restrained sizes, yielding new pi-pi stacking and fast exciton quenching. The temperature of the tumor area can rise to more than 70 degrees under NIR irradiation, which can effectively ablate a tumor. Read more »
Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease
Researchers describe potent small-molecule inhibitors that are neuroprotective in preclinical models of nerve injury and disease. The cover depicts the destruction of an axon by the enzyme SARM1, shown disproportionately large to convey its catastrophic role in driving degeneration once it is activated upon injury. Read more »
Andrea Taylor, Senior Administrator
As a member of the business administration team, Andrea Taylor is involved in many processes across the ALS—work that draws on her previous roles in hospitality. She has also lent her musical talents to our User Meetings, so be sure to check out the music videos. Read more »
Advanced Light Source Upgrade Approved to Start Construction
The ALS has received federal approval to start construction on an upgrade that will boost the brightness of its x-ray beams at least a hundredfold. The DOE approval, known as Critical Decision 3 (CD-3), formally releases funds for purchasing, building, and installing upgrades to the ALS. Read more »
Spring 2023 ALS Doctoral & Postdoctoral Fellowship Applications Open
ALS Doctoral and Postdoctoral Fellowships allow researchers to spend a year in residence at Berkeley Lab working at the frontier of synchrotron radiation research and helping advance state-of-the-art techniques and applications. The next application cycle closes December 9, 2022. Read more »
Vote for Your 2023 UEC Representatives
The Advanced Light Source Users’ Executive Committee (UEC) invites you to participate in the election of six new UEC members to represent the ALS community. The new members will take office for a three-year term beginning January 1, 2023. View candidate statements and submit your votes by 11:59 p.m. Pacific Time on Thursday, December 1. Read more »
ALS Staff Honored with 2022 Berkeley Lab Director’s Awards
Several ALS staff were recognized by Berkeley Lab Director Mike Witherell at the annual Director’s Awards ceremony on November 10. They include Steve Kevan, Jonathan Slack (as part of the Infant Warmer Team), and the ALS Structural Biology Beamline Team. Read more »
Daniela Leitner Elected APS Fellow
ALS-U’s Daniela Leitner has been elected a fellow of the American Physical Society for seminal contributions to a better understanding of ECR (electron-cyclotron-resonance) sources and pioneering the development of the fully superconducting ECR source VENUS, which remains the ECR community technology standard for high beam intensities. Read more »
Crossing from One to Two Dimensions in a Single Material
Low-dimensional materials exhibit excellent properties for use in next-generation electronic devices. Now, researchers have discovered an ideal platform for tuning between 1D and 2D physics, expanding the possibilities for device engineering and offering a versatile platform for the exploration of intriguing low-dimensional physics. Read more »
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