Protein structures obtained in part at the ALS helped researchers to increase the potency of simplified antibodies (nanobodies) designed to neutralize SARS-CoV-2. Stable enough to be used in inhalers or nasal sprays, the nanobodies offer a new option, aside from injected vaccines, for COVID-19 prevention and treatment. Read more »
Footprinting Technique Gives ALS Users New Insights
The x-ray footprinting (XFP) technique developed at ALS Beamline 5.3.1 gives researchers a powerful tool for the study of macromolecular structures and dynamics of proteins and nucleic acids in solution. Read more »