Often the full impact of a scientific discovery takes decades to realize, during which the research is developed further and adopted by other scientists. Such was the case for the work of biochemist Paul Modrich, one of three recipients of this year’s Nobel Prize in Chemistry. Berkeley Lab’s Advanced Light Source was a core resource Modrich used to build on his earlier work. Read more »
Protein Instability and Lou Gehrig’s Disease
A new study uses small-angle x-ray scattering as well as several advanced biophysical techniques to link protein instability to the progression of a lethal degenerative disease: amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Read more »
In Situ X-Ray Scattering Helps Optimize Printed Solar Cells
Printable plastic solar cells are a potential source of inexpensive renewable energy, but the transition from lab to factory results in decreased efficiency. Now, for the first time, a miniature solar-cell printer installed in a beamline allows researchers to use x-ray diffraction and scattering to figure out why. Read more »
New ALS Technique Guides IBM in Next-Generation Semiconductor Development
A new measurement technique developed at the ALS is helping guide the semiconductor industry in next-generation nanopatterning techniques. NIST and IBM researchers collaborated on the technique, which allows scientists to evaluate the 3D buried features inside a film. The ALS is currently the only place in the world that has such capability.
The Molecular Ingenuity of a Unique Fish Scale
ALS research has shown how the scales of a freshwater fish found in the Amazon Basin can literally re-orient themselves in real time to resist force, in essence creating an adaptable body armor. Read more »
Self-Assembly of “S-Bilayers”, a Step Toward Expanding the Dimensionality of S-Layer Assemblies
Protein-based assemblies with ordered nanometer-scale features in three dimensions are of interest as functional nanomaterials but are difficult to generate. Here we report that a truncated S-layer protein assembles into stable bilayers, which we characterized using cryogenic-electron microscopy, tomography, and X-ray spectroscopy. Read more »
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