Antimony is considered a priority environmental pollutant by the EPA. The ant operon of the antimony-mining bacterium, C. testosterone, confers resistance to Sb(III). The operon is regulated by the product of the first gene in the operon, antR. This is the first report of the structure and binding properties of antR, with high selectivity for environmental antimony. Read more »
All News & Updates
Sifting through Fragments for COVID-19 Treatments
COVID-19 vaccines are essential for preventing serious disease, but the identification of new drugs is still necessary for the treatment of patients who become sick as a result of SARS-CoV-2 infection. Here, scientists used computational docking and crystallography to screen large numbers of small molecules for potential use in drug compounds. Read more »
September 1 Proposal Deadline and COVID updates
The ALS is committed to supporting the science of our users, and we’re looking forward to welcoming back more on-site users this fall while continuing to support remote experiments. Please review the requirements for access to the ALS and remember to submit your proposals for the next cycle by 11:59 p.m. Pacific on September 1. Read more »
This Exotic Particle Had an Out-of-Body Experience; These Scientists Took a Picture of It
Scientists have taken the clearest picture yet of electronic particles that make up a mysterious magnetic state called a quantum spin liquid (QSL), in which electrons decompose into spin-like particles (spinons) and charge-like particles (chargons). The achievement could facilitate the development of superfast quantum computers and energy-efficient superconductors. Read more »
Scientist at Berkeley Lab Played a Hand in “Inescapable” COVID-19 Antibody Discovery
An antibody therapy that appears to neutralize all known SARS-CoV-2 strains—including newly emerged mutants that can now “escape” from previous antibody therapies—was developed with a little help from structural biologist Jay Nix. His work helped generate detailed structural maps of how antibodies bind to the spike protein, enabling the selection of promising contenders. Read more »
Extreme Ultraviolet Second Harmonic Generation Spectroscopy in a Polar Metal
Berger et al. utilize extreme ultraviolet, second-harmonic generation (XUV-SHG) spectroscopy to investigate the polar metal phase of lithium osmate (LiOsO3), where the coexistence of polarity and metallicity is unexpected. As the first demonstration of XUV-SHG spectroscopy around a phase transition, these results pave the way for using nonlinear XUV methods to investigate broken symmetry from an element-specific perspective. Read more »
Assembly of the SARS-CoV-2 Replication Mechanism
Using a multimodal approach that included x-ray scattering at the ALS, researchers determined how components of the SARS-CoV-2 replication mechanism fit together. A better understanding of how this protein complex works provides insight into potential structural or functional weak spots to exploit for drug development. Read more »
September 1 Deadline for General User Proposals
The User Office is accepting new General User Proposals (GUPs) from scientists who wish to conduct research at the ALS in the 2022-1 (January–July) cycle. The deadline for submissions is September 1, 2021. Applicants are reminded that they may request joint access to the Molecular Foundry, a nanoscience user facility at Berkeley Lab, to support their ALS activities. Read more »
Na Hyun Jo, Materials Sciences Postdoc
Na Hyun Jo has only been at Berkeley Lab for five months, but she’s already helping to organize the Energy Sciences Area Science Hour. Find out more about her research and what inspired her to become a scientist. Read more »
David Prendergast Wins 2021 Shirley Award
David Prendergast, an internationally recognized computational scientist whose first-principles calculations of x-ray spectra have helped with the interpretation of countless experiments done at the ALS, has been awarded the 2021 Shirley Award for Outstanding Scientific Achievement by the ALS Users’ Executive Committee. Read more »
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