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Actor in a Supporting Role: Substrate Effects on 2D Layers

ALS studies highlighted interactions that can occur between technologically intriguing 2D materials and the substrates that physically support them. The results provide important insights into the issue of non-negligible interlayer coupling and demonstrate the potential for tuning single-layer properties through substrate engineering. Read more »

March 3 Deadline for General User Proposals

The User Office is accepting new General User Proposals (GUPs) from scientists who wish to conduct research at the ALS in the 2021-2 (August–December) cycle. The deadline for submissions is March 3, 2021. Applicants are reminded that they may request joint access to the Molecular Foundry, a nanoscience user facility at Berkeley Lab, to support their ALS activities. Read more »

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells

A number of clinically validated drugs have been developed by repurposing the CUL4-DDB1-CRBN-RBX1 (CRL4CRBN) E3 ubiquitin ligase complex with molecular glue degraders to eliminate disease-driving proteins. Here, we present the identification of a first-in-class GSPT1-selective cereblon E3 ligase modulator, CC-90009, that targets acute myeloid leukemia blasts and leukemia stem cells. Read more »

A Detailed Look Inside Tsetse Flies

To better understand the unique reproductive biology of tsetse flies, which are carriers of the parasites that cause a deadly infection known as African sleeping sickness, researchers explored the intact organs and tissues of tsetse flies using a powerful 3D x-ray imaging technique at Berkeley Lab’s Advanced Light Source. Read more »

Identifying Ionic and Electronic Charge Transfer at Oxide Heterointerfaces

Researchers identified how ion and electron transfer naturally balance at the LaAlO3/SrTiO3 oxide heterointerface, affecting the band alignment and magnetic signature of the interface. The results show that Sr ions are more mobile at the interface than in the bulk, implicating a high importance of ionic charge transfer in oxide heterostructures. Read more »

Materials from Town Hall on Shutdown Schedules Now Available

On January 26, the ALS held a town hall on the schedule for upcoming long shutdowns. The event provided up-to-date information on the schedule, explained the motivations behind decisions, and discussed principles and strategies for future decision-making. Slides and a recording from the event, as well as an FAQs document, are posted to the ALS website. Read more »

2021 Update from ALS Director Steve Kevan

Steve Kevan reflects on the resilience of the ALS community over the past year and the progress we’ve continued to make, from timely COVID research to remote access on a variety of beamlines. As we look to the future, the continued efforts of the whole team will set us up for impactful science during and after the ALS Upgrade Project. Read more »

2D MXene Shows Evidence of a Magnetic Transition

A variety of experiments, including ALS x-ray studies, provided direct evidence of a magnetic transition in a 2D compound called a MXene (pronounced “maxene”). The finding adds new functionality to a family of materials with numerous ways to fine-tune properties for applications ranging from spintronic devices to electromagnetic shielding. Read more »PPT-icon-35 PDF-icon-35

M. Zahid Hasan Honored with DOE’s Prestigious Lawrence Award

The U.S. Department of Energy honored Hasan for “experiments using advanced spin-angle-resolved photoemission spectroscopy which led to seminal discoveries of new phases of matter and new fermionic quasiparticles.” Hasan is a longtime ALS user and a pioneer in the field of topological materials. Read more »

Johanna Nelson Weker, Users’ Executive Committee Chair

This year’s Users’ Executive Committee chair first used synchrotrons as a grad student and loved the experience so much she eventually became a beamline scientist at SSRL. She’s excited to work closely with the user community during the ALS Upgrade and is well versed in post-beamtime food options in Berkeley. Read more »