Scientists have found a way to improve the stability of an essential antigenic protein to develop vaccines with higher efficacy for prevention of bacterial meningitis. Read more »
ALS Work Using Scattering/Diffraction
These techniques make use of the patterns of light produced when x-rays are deflected by the closely spaced lattice of atoms in solids and are commonly used to determine the structures of crystals and large molecules such as proteins.
Luminescent MOFs for Mycotoxin Detection
Crystal diffractometry at ALS Beamline 11.3.1 helped scientists develop and understand a new, highly sensitive luminescent metal–organic framework for mycotoxin detection. Read more »
Conduction Along Magnetic Interfaces could Improve Memory Devices
Scientists have provided the first direct evidence of a controversial phenomenon: the boundaries between magnetic regions in an electrical insulator can become electrically conductive. This discovery can potentially lead to improvements in future memory storage devices. Read more »
Weaving of organic threads into a crystalline covalent organic framework
Threads made from organic molecules linked by strong covalent bonds were used to weave a 3D covalent organic framework with unusual dynamical and mechanical properties. This molecular weaving method will enable the production of materials with increased precision and functionality. Read more »
Foreign DNA Capture during CRISPR–Cas Adaptive Immunity
Using macromolecular crystallography at Beamline 8.3.1 at the ALS, Berkeley researchers discovered how CRISPR/Cas captures foreign DNA for the bacterial immune system. Read more »
On the Road to ANG Vehicles with Increased Driving Ranges
An international team of researchers, using gas adsorption studies, in situ powder x-ray diffraction, and single-crystal x-ray diffraction, showed that there is a way to develop a new flexible metal–organic framework (MOF) material for enhanced natural gas storage on vehicles. Read more »
A New Pathway for Radionuclide Uptake
Scientists have reported a major advance in understanding the biological chemistry of radioactive metals, opening up new avenues of research into strategies for remedial action in the event of possible human exposure to nuclear contaminants. Read more »
Following the Morphology Formation In Situ in Printed Active Layers for Organic Solar Cells
Time-resolved scattering measurements reveal the complete solidification process inside the photoactive layer of an organic solar cell. With an industrial slot-die coater integrated into the beamline, aggregation and crystallization processes can be tracked to reveal the structure-function relationships in the final thin film. Read more »
Binding Behavior of Dopamine Transporter Key to Understanding Chemical Reactions in the Brain
Scientists working at the ALS recently solved the crystallographic structures of several amine transporters in an effort to better understand why the human brain responds to chemicals like dopamine and serotonin. What they found will help in the design of drugs to treat many neurological diseases, and may also lead to a better understanding of how addiction to abused drugs such as cocaine can be managed. Read more »
Custom Organic Electronics Out of the Printer
Using in situ x-ray characterization and a custom-made slot-die coater at Beamline 7.3.3, the cross-linking of polymer molecules in the active layer of an organic solar cell during the printing process could be observed.
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