Scientists used small-molecule x-ray crystallography to verify and characterize the first non-functionalized fullerene with a heptagonal ring in the cage. This new molecule changes the definition of a classical fullerene and expands the range of structural possibilities for endohedral fullerenes. Read more »
ALS Work Using Scattering/Diffraction
These techniques make use of the patterns of light produced when x-rays are deflected by the closely spaced lattice of atoms in solids and are commonly used to determine the structures of crystals and large molecules such as proteins.
What Goes Up, Must Come Down (and Sometimes Gets Stuck)
High-pressure experiments at Beamline 12.2.2 on ferropericlase—the presumed weakest mineral found in the Earth’s lower mantle—help explain why subducted slabs of Earth’s crust stall at a depth of around 1000 km (~625 miles). Read more »
Peptoid Nanosheets Offer a Diversity of Functionalities
Researchers at the ALS have recently observed peptoid nanosheets as they self-assemble at an oil–water interface. This development opens the door to designing peptoid nanosheets of increasing complexity and functionality for a broad range of applications, including improved chemical sensors and separators, and safer, more effective drug-delivery vehicles. Read more »
A Milky Mystery: The Case of the Casein Micelles
We all know that milk contains important nutrients such as calcium and protein that help build bones and muscle. But how much do we really know about these ingredients at the molecular level? To learn more, scientists from New Zealand and Australia came to the ALS to x-ray some milk.
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Protein Instability and Lou Gehrig’s Disease
A new study uses small-angle x-ray scattering as well as several advanced biophysical techniques to link protein instability to the progression of a lethal degenerative disease: amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Read more »
Terra Sigillata: Evolution of Roman Ceramics Reflect Changes in Technology, Life
Ancient terra sigillata ceramics were the most famous and ubiquitous Roman tableware, yet when their manufacturing spread to other locations, some of the ceramics’ characteristics changed. Researchers from France and the ALS traced the changes.
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In Situ X-Ray Scattering Helps Optimize Printed Solar Cells
Printable plastic solar cells are a potential source of inexpensive renewable energy, but the transition from lab to factory results in decreased efficiency. Now, for the first time, a miniature solar-cell printer installed in a beamline allows researchers to use x-ray diffraction and scattering to figure out why. Read more »
Rare Iron Oxide in Ancient Chinese Pottery
New analysis of ancient Jian ware reveals that the distinctive pottery contains an unexpected and highly unusual form of iron oxide. This rare compound was only recently discovered and characterized by scientists and so far has been extremely difficult to create with modern techniques.
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Brain Receptor Structures Key to Future Therapeutics
Neurotransmitter receptor proteins are critical to learning and memory. Mutations are associated with neurological and neuropsychiatric conditions including Alzheimer’s, epilepsy, and autism. Structures of two such receptors, solved by x-ray crystallography, provide a blueprint for the development of therapeutics. Read more »
New ALS Technique Guides IBM in Next-Generation Semiconductor Development
A new measurement technique developed at the ALS is helping guide the semiconductor industry in next-generation nanopatterning techniques. NIST and IBM researchers collaborated on the technique, which allows scientists to evaluate the 3D buried features inside a film. The ALS is currently the only place in the world that has such capability.