The lack of information as to whether a genetic mutation is pathogenic or benign causes ambiguity during clinical diagnosis and hinders appropriate treatment. Here, researchers use several techniques, including small‐angle x‐ray scattering, to help classify genetic variants associated with an increased predisposition to certain cancers. Read more »
Journal Covers
Comparative morphology of cheliceral muscles using high‐resolution X‐ray microcomputed‐tomography in palpimanoid spiders
Spiders are important predators in terrestrial ecosystems, yet we know very little about their principal feeding structures—the chelicerae—an extremely important aspect of spider biology. Here, using micro‐Computed‐Tomography scanning techniques, researchers perform a comparative study to examine cheliceral muscle morphology in six different spider specimens. Read more »
Pressure-driven band gap engineering in ion-conducting semiconductor silver orthophosphate
This work explores a novel method to tune the electronic band structures of active semiconductor photocatalysts to gain insight into structure–property relationships. Taking silver orthophosphate (Ag3PO4) as an example, a static pressure technique was applied to modulate the band gap and indirect–direct band character via altering its crystal structure and lattice parameters. Read more »
Spatial and Temporal Correlations of XY Macro Spins
Artificial spin-ice structures have become prototypical systems to study vector spin frustration at the microscale and have recently been expanded towards XY spin systems and fundamentally fascinating phase transitions. The illustration depicts the quasi long-range ordered vortex phase in a nano disk honeycomb lattice imaged by magnetization-sensitive photoemission electron microscopy. Read more »
Self‐Assembly of Large‐Area 2D Polycrystalline Transition Metal Carbides for Hydrogen Electrocatalysis
Xining Zang et al. develop a self‐assembly process to synthesize 2D transition metal carbides (TMCs). The metal ions (Mo, Co, W) self‐organize within a gelatin template into a lamellar nanostructure. Subsequent carbonization at moderate temperatures in a reducing atmosphere yields ultrathin 2D‐TMC sheets with high conductivity and rich active sites ideal for the hydrogen evolution reaction. Read more »
Magnetic Skyrmions: Current‐Induced Skyrmion Generation through Morphological Thermal Transitions in Chiral Ferromagnetic Heterostructures
Magnetic skyrmions are particle‐like chiral twists of the magnetization that promise advances in spin‐based data storage and logic device applications. In this article, researchers examine current‐induced generation of skyrmions in heavy‐metal/ferromagnet multilayers and show that Joule heat pulses can drive topological transitions in magnetic textures and enable skyrmion creation on nanosecond timescales. Read more »
Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters
The influenza M2 proton channel can bind to drugs and inhibitors. The ammonium groups of these compounds form hydrogen bonds with networks of ordered waters within the channel, and the adamantyl groups sterically block the diffusion of hydronium into the channel pore. Read more »
Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei
Recent super-resolution fluorescence microscopy studies have revealed significantly altered nuclear organization between normal lymphocyte nuclei and those of classical Hodgkin’s lymphoma. Reported here are the first near-field IR imaging of lymphocyte nuclei, and far-field IR imaging results of whole lymphocytes and nuclei from normal human blood. Read more »
Experimental Evidence of Chiral Ferrimagnetism in Amorphous GdCo Films
Harnessing high‐resolution Lorentz microscopy, Robert Streubel and co‐workers visualize chiral ferrimagnetic domain walls in amorphous films, revealing a composition dependence that potentially enables a temperature control of intrinsic domain wall properties. The reconstructed electron phase (magnetic induction) of achiral Bloch domain walls is shown here. Read more »
Reversible Fe(II) uptake/release by magnetite nanoparticles
The coexistence of magnetite and aqueous Fe2+ is common in anoxic subsurface environments and can have a great influence on important biogeochemical redox processes. This study demonstrates that the flow direction of electron equivalents in the form of Fe(II) across the magnetite–solution interface changes in a predictable fashion by altering solution pH, background Fe2+(aq) concentration, and magnetite loading. Read more »
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