NASA’s $200-million, seven-year-long Stardust mission returned to Earth thousands of tiny particles snagged from the coma of comet 81P/Wild 2. Four ALS beamlines and the researchers using them were among the hundreds of scientists and dozens of experimental techniques in facilities around the world that contributed to the preliminary examination of the first samples.
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First Detailed Look at RNA Dicer
Scientists have gotten their first detailed look at the molecular structure of an enzyme that Nature has been using for eons to help silence unwanted genetic messages: Dicer, an enzyme that plays a critical role in a process known as RNA interference.
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Snapshots of Ribozyme Reaction States Reveal Structural Switch
RNA, like protein, can sometimes function as an enzyme (ribozyme) to speed biochemical reaction rates. But how does RNA, a simple polymer, enhance reaction rates by at least a million fold? Researchers obtained the structures of a ribozyme trapped in different states of its catalytic cycle, showing how a change in the RNA conformation governs the reaction mechanism. Read more »
ALSNews Vol. 216
Originally published on February 19, 2003. Read more »
The Path of Messenger RNA through the Ribosome
Using x-ray crystallography, researchers directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 Å resolution. Image depicts the view down the crystallographic 4-fold axis of the 70S ribosome-mRNA-tRNA complex, showing the head-to-tail juxtaposition of the model mRNAs (red-orange) between adjacent ribosomes. Read more »
Crosslink Density of Superabsorbent Polymers
Researchers from The Dow Chemical Company teamed with academic colleagues to conduct x-ray spectromicroscopy studies of superabsorbent polymers (SAPs), materials with a wide range of applications, including disposable baby diapers. Dow has been able to use the results to help develop the process technology for a new SAP-manufacturing plant. Read more »