Early detection of Alzheimer’s disease may soon be within reach, thanks to spectral phenotyping. Using infrared spectroscopy, Berkeley Lab researchers developed this technique to detect the subtle biochemical changes in a “cellular fingerprint” that is characteristic of the devastating disease. Read more »
Cell ‘Fingerprinting’ Could Yield Long-Awaited Alzheimer’s Disease Diagnostic
A new application of infrared spectromicroscopy analyzes cells for signs of Alzheimer’s disease by measuring how the molecules in cells vibrate upon exposure to infrared light. The vibrational profile of each sample is so distinct and the difference between diseased and healthy cell samples is so visible that researchers liken the process to “cellular fingerprinting.” Read more »
Laser-Induced Cooperative Transition in Molecular Electronic Crystal
The cooperative tuning of a supramolecular electronic crystal enables access to a long-lived hidden conducting phase with a broad temperature range. Researchers demonstrate a dynamic and cooperative phase in K-TCNQ, with the control of pulsed electromagnetic excitation. A dedicated charge–spin–lattice decoupling is required to activate and subsequently stabilize the non-equilibrium phase. Read more »
2D Electronics Get an Atomic Tuneup
Researchers demonstrated a promising avenue for controlling atomic ordering in semiconductor alloys by engineering frustrated interactions in a 2D transition metal dichalcogenide (TMD). The work could lead to improved semiconductor performance for next-generation electronics such as optoelectronics, thermoelectrics, and sensors. Read more »
Survival of T. rex Microvascular Structures from Deep Time
Researchers used several analytical techniques at the ALS to demonstrate how soft-tissue structures may be preserved in dinosaur bones, countering long-standing scientific dogma that protein-based body parts cannot survive more than one million years. Read more »
Can Minerals in the Earth’s Lower Mantle Store Water?
Earth is considered a watery planet, simply by virtue of the fact that 71% of its surface is covered by oceans. But researchers have discovered that, in the massive volume of material in Earth’s interior, minerals can serve as an important water reservoir, providing a new perspective on our planet’s water budget. Read more »
Berkeley Lab Helps Reveal How Dinosaur Blood Vessels Can Preserve Through the Ages
A team of scientists used infrared and x-ray imaging performed at the Advanced Light Source to determine the chemical mechanisms that allow soft tissue structures to persist in dinosaur bones—countering the long-standing scientific dogma that protein-based body parts can’t survive more than 1 million years. Read more »
Scientists Explore Egyptian Mummy Bones With X-Rays and Infrared Light to Gain New Insight on Ancient Life
Researchers from Cairo University worked with teams at the ALS to study soil and bone samples dating back 4,000 years. The experiments are casting a new light on Egyptian soil and ancient mummified bone samples that could provide a richer understanding of daily life and environmental conditions thousands of years ago. Read more »
Clues to the Solar System’s Original “Bricks and Mortar”
In comet dust, researchers discovered composite organic-inorganic mineral grains that are likely to be the original “bricks and mortar” of the solar system. “Forensic” samples preserved from the birth of the solar system allow investigations into the nature of the atomic and molecular ancestry of the terrestrial planets and life on Earth. Read more »
From Moon Rocks to Space Dust: Berkeley Lab’s Extraterrestrial Research
Berkeley Lab has a well-storied expertise in exploring samples of extraterrestrial origin. This research—which has helped us to understand the makeup and origins of objects within and beyond our solar system—stems from long-standing core capabilities in structural and chemical analyses and measurement at the microscale and nanoscale. Read more »
