Using a multimodal approach that included x-ray scattering at the ALS, researchers determined how components of the SARS-CoV-2 replication mechanism fit together. A better understanding of how this protein complex works provides insight into potential structural or functional weak spots to exploit for drug development. Read more »
Nanoscale Metallic Particles Detected in Brain Tissue
Researchers detected nanoscale deposits of elemental copper and iron in brain tissues isolated from Alzheimer’s disease subjects. The discovery suggests new directions of study to determine the role that elemental metals might play in neurochemistry, neurobiology, and the development of neurodegenerative disease. Read more »
Tuning Semimetallicity Using Thin Films and Interfaces
With support from ALS data, scientists gained new insight into a semimetal’s unusual electronic behavior. The work lays out a basic strategy for engineering the band structures of semimetallic compounds using dimensional confinement and reveals a new way of creating two-dimensional electron/hole gases by exploiting interfacial bonding. Read more »
Programmable Micromagnets for Single-Cell Sorting
Researchers demonstrated that electrically induced mechanical strain can control the magnetic state of tiny magnets used to sort biological cells. The work lays the foundation for a programmable, single-cell sorting platform to support a wide variety of biotechnology applications, including personalized cancer treatments. Read more »
A Properly Tailored Tail Boosts Solar-Cell Efficiency
With the help of structural insights from the ALS, researchers optimized the fit between organic and inorganic ions in a perovskite solar-cell material. The work increased the material’s power-conversion efficiency and stability and opens up a new avenue for improving the current-carrier dynamics of a promising class of materials. Read more »
Study Shines New Light on Li-Battery Cathode Materials
Researchers clarified key reaction mechanisms in a Li-battery cathode material, revealing its surprising utility as a catalyst for next-gen batteries. The work refutes widely held ideas about reversible reactions in a highly debated material for Li-based batteries and expands the range of materials suitable for use in high-power batteries and fuel cells. Read more »
Tuning of One Atomic Layer Unlocks Catalytic Pathway
An atomically precise surface probe helped researchers discover that a catalyst can be activated by tuning the composition of just one atomic surface layer. The work sharpens our understanding of how surface changes can improve the production of hydrogen fuel from water using efficient catalysts made of inexpensive materials. Read more »
Mystery Protein Helps COVID–19 Avoid Immunity
Using the Advanced Light Source (ALS), researchers solved the structure of ORF8, a protein specific to SARS-CoV-2. Understanding the structure of ORF8 opens the door to therapy studies targeting SARS-CoV-2, the virus responsible for causing COVID-19. Read more »
Probing Composite Materials to Make Better Batteries
Researchers found that when an ion-conducting polymer composite is placed in an electric field, it forms ion-rich hotspots that continue to grow for hours after the field is removed. The study opens a new path to understanding the dynamic structure of composite materials for smaller, lighter batteries. Read more »
2D MXene Shows Evidence of a Magnetic Transition
A variety of experiments, including ALS x-ray studies, provided direct evidence of a magnetic transition in a 2D compound called a MXene (pronounced “maxene”). The finding adds new functionality to a family of materials with numerous ways to fine-tune properties for applications ranging from spintronic devices to electromagnetic shielding. Read more »
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