Sickle cell disease (SCD), which affects millions of people worldwide, has traditionally been treated with a cytotoxic drug that has a range of negative side effects and variable patient response. Bay Area biopharmaceutical company Global Blood Therapeutics (GBT) is on a mission to develop a better treatment and is using the ALS to help. Read more »
Intel, the world’s largest semiconductor chip maker, has been using the tomography capabilities at the ALS to image their microelectronic packages in 3D at high resolution with short throughput time, providing valuable information for both failure analysis and product development and proving that synchrotrons are an insightful tool for this type of imaging. Read more »
Developing ceramic matrix composites (CMCs) to replace the metal alloys traditionally used in jet engines has been a goal for the aviation industry for decades. For more than a year, GE Aviation has used the tomography capabilities at ALS Beamline 8.3.2 to gain insight into their CMC materials, guiding their engineering and design efforts. Read more »
An industrial collaboration between Hummingbird Scientific and a team of researchers from the ALS, SLAC, Berkeley Lab, Stanford University, and other institutions has resulted in a new x-ray microscopy platform that gives scientists the ability to image nanoscale changes inside lithium-ion battery particles in real time as they charge and discharge. Insights obtained from the imaging platform have already provided surprising new insights and could help researchers improve batteries for electric vehicles as well as smart phones, laptops, and other devices. Read more »
A beamstop device recently developed at the ALS has successfully combined two essential crystallographic functions–capturing the damaging portion of the beam while simultaneously monitoring its intensity–into a single miniaturized package. The technology has been licensed and launched commercially and is also a finalist for an R&D 100 Award. Read more »
For the past eight years, Hewlett Packard Labs, the central research organization of Hewlett Packard Enterprise, has been using cutting-edge ALS techniques to advance some of their most promising technological research, including vanadium dioxide phase transitions and atomic movement during memristor operation. Read more »
A collaboration between Bay Area company aBeam Technologies, the ALS, and the Molecular Foundry is bringing cutting-edge metrology instrumentation to the semiconductor market, which will enable a new level of quality control. Read more »
Type 2 diabetes mellitus (T2DM), characterized by abnormally high blood glucose levels, affects hundreds of millions of people worldwide. In the pursuit to better treat this disease, the human receptor protein GPR40 has been identified by pharmaceutical company Takeda as a potential new drug target.
A new measurement technique developed at the ALS is helping guide the semiconductor industry in next-generation nanopatterning techniques. NIST and IBM researchers collaborated on the technique, which allows scientists to evaluate the 3D buried features inside a film. The ALS is currently the only place in the world that has such capability.
When Rachel Haurwitz joined UC Berkeley biology professor Jennifer Doudna’s lab in 2007 as a graduate student, little did the two women know that the interesting bacterial immune system they were studying would be the subject of news headlines and the basis for a biotech startup just a few years later.